Primary HBB gene mutation severity and long‐term outcomes in a global cohort of β‐thalassaemia

Author:

Musallam Khaled M.1ORCID,Vitrano Angela2ORCID,Meloni Antonella3ORCID,Addario Pollina Sebastiano4,Di Marco Vito5,Hussain Ansari Saqib6,Filosa Aldo7,Ricchi Paolo7ORCID,Ceci Adriana8,Daar Shahina910,Vlachaki Efthymia11,Singer Sylvia T.12,Naserullah Zaki A.13,Pepe Alessia3,Scondotto Salvatore4,Dardanoni Gabriella4,Karimi Mehran14ORCID,El‐Beshlawy Amal15,Hajipour Mahmoud16,Bonifazi Fedele8,Vichinsky Elliott12,Taher Ali T.17ORCID,Sankaran Vijay G.181920,Maggio Aurelio2,

Affiliation:

1. Thalassemia Center Burjeel Medical City Abu Dhabi United Arab Emirates

2. Campus of Haematology Franco and Piera Cutino AOOR Villa Sofia‐V. Cervello Palermo Italy

3. MRI Unit Fondazione G. Monasterio CNR‐Regione Toscana Pisa Italy

4. D.A.S.O.E Regione Siciliana Palermo Italy

5. Department of Promozione della Salute Materno Infantile Medicina Interna e Specialistica di Eccellenza (PROMISE) University of Palermo Palermo Italy

6. Department of Pediatric Haematology & Molecular Medicine National Institute of Blood Diseases and Bone Marrow Transplantation Karachi Pakistan

7. Rare Blood Cell Disease Unit "Cardarelli" Hospital Naples Italy

8. Fondazione per la Ricerca Farmacologica Gianni Benzi Onlus Valenzano (BA) Italy

9. Department of Haematology College of Medicine and Health Sciences Sultan Qaboos University Muscat Sultanate of Oman

10. Wallenberg Research Centre Stellenbosch Institute for Advanced Study Stellenbosch University Stellenbosch South Africa

11. Thalassaemia Unit Ippokratio University Hospital Thessaloniki Greece

12. Division of Hematology‐Oncology Department of Pediatrics University of California San Francisco UCSF Benioff Children's Hospital Oakland Oakland CA USA

13. Dammam Maternity and Child Hospital Dammam Saudi Arabia

14. Haematology Research Center Shiraz University of Medical Sciences Shiraz Iran

15. Department of Pediatric Haematology Faculty of Medicine Cairo University Cairo Egypt

16. Pediatric Gastroenterology, Hepatology and Nutrition Research Center Research Institute for Children’s Health Shahid Beheshti University of Medical Sciences Tehran Iran

17. Department of Internal Medicine American University of Beirut Medical Center Beirut Lebanon

18. Division of Hematology/Oncology Boston Children's Hospital and Department of Pediatric Oncology Dana‐Farber Cancer Institute Harvard Medical School Boston MA USA

19. Broad Institute of MIT and Harvard Cambridge MA USA

20. Harvard Stem Cell Institute Cambridge MA USA

Publisher

Wiley

Subject

Hematology

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