Improved Anti-Emetic Efficacy of 5-HT3Receptor Antagonists in Cancer Patients with Genetic Polymorphisms of ABCB1 (MDR1) Drug Transporter

Author:

Zoto Teuta1,Kilickap Saadettin2,Yasar Umit1,Celik Ismail2,Bozkurt Atilla1,Babaoglu Melih Onder1

Affiliation:

1. Department of Pharmacology; Faculty of Medicine; Hacettepe University; Ankara Turkey

2. Division of Medical Oncology; Department of Internal Medicine; Faculty of Medicine; Hacettepe University; Ankara Turkey

Funder

TUBA The Turkish Academy of Sciences

TUBITAK the Scientific and Technological Research Council of Turkey

Publisher

Wiley

Subject

Pharmacology,Toxicology,General Medicine

Reference28 articles.

1. Nausea and emesis remain significant problems of chemotherapy despite prophylaxis with 5-hydroxytryptamine-3 antiemetics: a University of Rochester James P. Wilmot Cancer Center Community Clinical Oncology Program Study of 360 cancer patients treated in the community;Hickok;Cancer,2003

2. Initial control of chemotherapy-induced nausea and vomiting in patient quality of life;Morrow;Oncology (Williston Park),1998

3. Anti-emetic therapy in cancer chemotherapy: current status;Herrstedt;Basic Clin Pharmacol Toxicol,2007

4. Best practice management of CINV in oncology patients: II. Antiemetic guidelines and rationale for use;Wickham;J Support Oncol,2010

5. Evidence-based recommendations for cancer nausea and vomiting;Naeim;J Clin Oncol,2008

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