Non-Clinical Pharmacokinetics, Prediction of Human Pharmacokinetics and First-in-Human Dose Selection for CNTO 5825, an Anti-Interleukin-13 Monoclonal Antibody-Reference-Cited by-同舟云学术

Non-Clinical Pharmacokinetics, Prediction of Human Pharmacokinetics and First-in-Human Dose Selection for CNTO 5825, an Anti-Interleukin-13 Monoclonal Antibody

Published:2015-03 Issue: Volume: Page:n/a-n/a
ISSN:1742-7835
Container-title:Basic & Clinical Pharmacology & Toxicology
language:en
Short-container-title:Basic Clin Pharmacol Toxicol

Author:

Nnane Ivo P.¹,Xu Zhenhua¹,Zhou Honghui¹,Davis Hugh M.¹

Affiliation:

1. Biologics Clinical Pharmacology; Janssen Pharmaceutical Research and Development; LLC; Spring House PA USA

Publisher

Wiley

Subject

Pharmacology,Toxicology,General Medicine

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/bcpt.12391/fullpdf

Reference36 articles.

1. IL-13 effector functions;Wynn;Annu Rev Immunol,2003

2. Interleukin-13 in asthma pathogenesis;Wills-Karp;Immunol Rev,2004

3. Interleukin-13: central mediator of allergic asthma;Wills-Karp;Science,1998

4. Biology and therapeutic potential of the interleukin-4/interleukin-13 signaling pathway in asthma;Corry;Am J Respir Med,2002

5. Untangling the complex web of IL-4- and IL-13-mediated signaling pathways;Wills-Karp;Sci Signal,2008

Cited by 12 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The IL-4/-13 Axis and Its Blocking in the Treatment of Atopic Dermatitis;Journal of Clinical Medicine;2022-09-24

2. A Single Animal Species-Based Prediction of Human Clearance and First-in-Human Dose of Monoclonal Antibodies: Beyond Monkey;Antibodies;2021-09-05

3. The Current Application of LC-MS/MS in Pharmacokinetics of Traditional Chinese Medicines (Recent Three Years): A Systematic Review;Current Drug Metabolism;2020-12-30

4. Simple Approach to Accurately Predict Pharmacokinetics of Therapeutic Monoclonal Antibodies after Subcutaneous Injection in Humans;Clinical Pharmacokinetics;2020-08-11

5. Predicting Method for the Human Plasma Concentration–Time Profile of a Monoclonal Antibody from the Half-life of Non-human Primates;Biological and Pharmaceutical Bulletin;2020-05-01