Advanced oxidation protein products induce apoptosis of human chondrocyte through reactive oxygen species-mediated mitochondrial dysfunction and endoplasmic reticulum stress pathways

Author:

Ye Wenbin1,Zhu Siyuan1,Liao Congrui1,Xiao Jun2,Wu Qian1,Lin Zhen1,Chen Jianting1

Affiliation:

1. Department of Orthopaedic Spinal Surgery; Nanfang Hospital; Southern Medical University; 1838 North Guangzhou Avenue Guangzhou 510515 China

2. Department of Orthopedic Joint Surgery; Nanfang Hospital; Southern Medical University; 1838 North Guangzhou Avenue Guangzhou 510515 China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference38 articles.

1. Oxidation in rheumatoid arthritis;Hitchon;Arthritis. Res. Ther.,2004

2. Occurrence of oxidatively modified proteins: an early event in experimental acute pancreatitis;Reinheckel;Free Radic. Biol. Med.,1998

3. Adriamycin induces protein oxidation in erythrocyte membranes;DeAtley;Pharmacol. Toxicol.,1998

4. Advanced oxidation protein products as a novel marker of oxidative stress in uremia;Witko-Sarsat;Kidney Int.,1996

5. Advanced oxidation protein products as novel mediators of inflammation and monocyte activation in chronic renal failure;Witko-Sarsat;J. Immunol.,1998

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