Comorbidity, not patient age, is associated with impaired safety outcomes in vedolizumab- and ustekinumab-treated patients with inflammatory bowel disease-a prospective multicentre cohort study

Author:

Asscher Vera E. R.1ORCID,Biemans Vince B. C.23ORCID,Pierik Marieke J.3,Dijkstra Gerard4,Löwenberg Mark5,van der Marel Sander6,de Boer Nanne K. H.5,Bodelier Alexander G. L.7,Jansen Jeroen M.5,West Rachel L.8,Haans Jeoffrey J. L.3,van Dop Willemijn A.2,Weersma Rinse K.4,Hoentjen Frank2,Maljaars P. W. Jeroen1ORCID,

Affiliation:

1. Leiden the Netherlands

2. Nijmegen the Netherlands

3. Maastricht the Netherlands

4. Groningen the Netherlands

5. Amsterdam the Netherlands

6. The Hague the Netherlands

7. Breda the Netherlands

8. Rotterdam the Netherlands

Publisher

Wiley

Subject

Pharmacology (medical),Gastroenterology,Hepatology

Reference29 articles.

1. Epidemiology and natural history of inflammatory bowel diseases;Cosnes;Gastroenterology,2011

2. Cardiometabolic comorbidities in RA and PsA: lessons learned and future directions;Ferguson;Nat Rev Rheumatol,2019

3. Patients with inflammatory bowel disease have an increased risk of myocardial infarction: a nationwide study;Choi;Aliment Pharmacol Ther,2019

4. Mortality in adult-onset and elderly-onset IBD: a nationwide register-based cohort study 1964-2014;Olén;Gut,2020

5. Older age and steroid use are associated with increasing polypharmacy and potential medication interactions among patients with inflammatory bowel disease;Parian;Inflamm Bowel Dis,2015

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