Inhibition of melatonin metabolism in humans induced by chemical components from herbs and effective prediction of this risk using a computational model

Author:

Wang Chao12,Huo Xiaokui1,Tian Xiangge1,Xu Min1,Dong Peipei1,Luan Zhilin1,Wang Xiaobo3,Zhang Baojing1,Zhang Bo2,Huang Shanshan1,Deng Sa1,Ma Xiaochi12

Affiliation:

1. Academy of Integrative Medicine, College of Pharmacy, Key Laboratory of Pharmacokinetic and Drug Transport of Liaoning; Dalian Medical University; Dalian China

2. Department of Neurosurgery; The Second Affiliated Hospital of Dalian Medical University; Dalian China

3. Department of Pharmacy and Traditional Chinese Medicine; Chinese People's Liberation Army 210 Hospital; Dalian China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Pharmacology

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