First‐in‐human study of the safety, tolerability, pharmacokinetics, and pharmacodynamics of ALPN‐101, a dual CD28/ICOS antagonist, in healthy adult subjects-Reference-Cited by-同舟云学术

First‐in‐human study of the safety, tolerability, pharmacokinetics, and pharmacodynamics of ALPN‐101, a dual CD28/ICOS antagonist, in healthy adult subjects

Published:2021-03-02 Issue:4 Volume:14 Page:1314-1326
ISSN:1752-8054
Container-title:Clinical and Translational Science
language:en
Short-container-title:Clin Transl Sci

Author:

Yang Jing¹,Lickliter Jason D.²,Hillson Jan L.¹,Means Gary D.¹,Sanderson Russell J.¹,Carley Kay¹,Tercero Almudena¹,Manjarrez Kristi L.¹,Wiley Jennifer R.¹,Peng Stanford L.¹

Affiliation:

1. Alpine Immune Sciences, Inc. Seattle Washington USA

2. Nucleus Network Melbourne Victoria Australia

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Biochemistry, Genetics and Molecular Biology,General Medicine,General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/cts.12983

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4. Orencia(abatacept) [package insert]. US Food and Drug Administration websitehttps://wwwaccessdatafdagov/drugsatfda_docs/label/2020/125118s194s199s225lblpdfAccessed June 17 2020.

5. The efficacy and safety of abatacept in patients with non-life-threatening manifestations of systemic lupus erythematosus: Results of a twelve-month, multicenter, exploratory, phase IIb, randomized, double-blind, placebo-controlled trial

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