Deferasirox (ICL670A) effectively inhibits oesophageal cancer growthin vitroandin vivo

Author:

Ford SJ1,Obeidy P2,Lovejoy DB2,Bedford M1,Nichols L1,Chadwick C1,Tucker O1,Lui GYL2,Kalinowski DS2,Jansson PJ2,Iqbal TH1,Alderson D1,Richardson DR2,Tselepis C1

Affiliation:

1. School of Cancer Sciences; Department of Medical & Dental Sciences; University of Birmingham; Birmingham; UK

2. Department of Pathology and Bosch Institute; University of Sydney; Sydney; NSW; Australia

Publisher

Wiley

Subject

Pharmacology

Reference54 articles.

1. Overexpression of cellular iron import proteins is associated with malignant progression of esophageal adenocarcinoma;Boult;Clin Cancer Res,2008

2. A role for iron in Wnt signalling;Brookes;Oncogene,2008

3. Cancer Research UK (CRUK) 2012 Oesophageal cancer statistics http://info.cancerresearchuk.org/cancerstats/types/oesophagus/

4. Long-term efficacy and safety of deferasirox;Cappellini;Blood Rev,2008

5. The new orally active iron chelator ICL670A exhibits a higher antiproliferative effect in human hepatocyte cultures than O-trensox;Chantrel-Groussard;Eur J Pharmacol,2006

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