Pharmacologic inhibition of <scp>LAT1</scp> predominantly suppresses transport of large neutral amino acids and downregulates global translation in cancer cells-Reference-Cited by-同舟云学术

Pharmacologic inhibition of LAT1 predominantly suppresses transport of large neutral amino acids and downregulates global translation in cancer cells

Published:2022-09-07 Issue:20 Volume:26 Page:5246-5256
ISSN:1582-1838
Container-title:Journal of Cellular and Molecular Medicine
language:en
Short-container-title:J Cellular Molecular Medi

Author:

Nishikubo Kou¹^ORCID,Ohgaki Ryuichi¹²^ORCID,Okanishi Hiroki¹,Okuda Suguru¹³^ORCID,Xu Minhui¹,Endou Hitoshi⁴,Kanai Yoshikatsu¹²^ORCID

Affiliation:

1. Department of Bio‐system Pharmacology, Graduate School of Medicine Osaka University Osaka Japan

2. Integrated Frontier Research for Medical Science Division, Institute for Open and Transdisciplinary Research Initiatives (OTRI) Osaka University Osaka Japan

3. Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences The University of Tokyo Tokyo Japan

4. J‐Pharma Co., Ltd Yokohama Japan

Funder

Japan Agency for Medical Research and Development

Japan Society for the Promotion of Science

Ministry of Education, Culture, Sports, Science and Technology

National Institutes of Biomedical Innovation, Health and Nutrition

Publisher

Wiley

Subject

Cell Biology,Molecular Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/jcmm.17553

Reference61 articles.

1. Hallmarks of Cancer: The Next Generation

2. The Emerging Hallmarks of Cancer Metabolism

3. Amino acids in cancer

4. Multifaceted role of branched-chain amino acid metabolism in cancer

5. mTOR at the nexus of nutrition, growth, ageing and disease

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