Exosome and epithelial–mesenchymal transition: A complex secret of cancer progression

Author:

Dhar Rajib1ORCID,Devi Arikketh1ORCID,Gorai Sukhamoy2ORCID,Jha Saurabh Kumar345ORCID,Alexiou Athanasios67ORCID,Papadakis Marios8

Affiliation:

1. Cancer and Stem Cell Biology Laboratory, Department of Genetic Engineering SRM Institute of Science and Technology Kattankulathur India

2. Rush University Medical Center Chicago Illinois USA

3. Department of Biotechnology, School of Engineering and Technology (SET) Sharda University Greater Noida India

4. Department of Biotechnology Engineering and Food Technology Chandigarh University Mohali India

5. Department of Biotechnology, School of Applied and Life Sciences (SALS) Uttaranchal University Dehradun India

6. Department of Science and Engineering, Novel Global Community Educational Foundation Hebersham New South Wales Australia

7. AFNP Med Wien Austria

8. Department of Surgery II University Hospital Witten‐Herdecke Witten Germany

Abstract

AbstractThis short communication will enlighten the readers about the exosome and the epithelial‐mesenchymal transition (EMT) related to several complicated events. It also highlighted the therapeutic potential of exosomes against EMT. Exosome toxicology, exosome heterogeneity, and a single exosome profiling approach are also covered in this article. In the future, exosomes could help us get closer to cancer vaccine and precision oncology.

Publisher

Wiley

Subject

Cell Biology,Molecular Medicine

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