Nicorandil regulates the macrophage skewing and ameliorates myofibroblasts by inhibition of RhoA/Rho-kinase signalling in infarcted rats

Author:

Lee Tsung-Ming1234,Lin Shinn-Zong56,Chang Nen-Chung47

Affiliation:

1. Cardiology Section; Department of Medicine; An-Nan Hospital; China Medical University; Tainan Taiwan

2. Department of Medicine; China Medical University; Taichung Taiwan

3. Cardiovascular Research Laboratory; China Medical University Hospital; Taichung Taiwan

4. Department of Internal Medicine; School of Medicine; College of Medicine; Taipei Medical University; Taipei Taiwan

5. Department of Neurosurgery; Tzu Chi University Hospital; Hualien Taiwan

6. Bioinnovation Center; Tzu Chi foundation; Hualien Taiwan

7. Division of Cardiology; Department of Internal Medicine; Taipei Medical University Hospital; Taipei Taiwan

Funder

An-Nan Hospital

Ministry of Science and Technology, Taiwan

Publisher

Wiley

Subject

Cell Biology,Molecular Medicine

Reference43 articles.

1. Interrelation of immunity and tissue repair or regeneration;Eming;Semin Cell Dev Biol,2009

2. Alternative activation of macrophages;Gordon;Nat Rev Immunol,2003

3. The chemokine system in diverse forms of macrophage activation and polarization;Mantovani;Trends Immunol,2004

4. Myofibroblasts and mechano-regulation of connective tissue remodelling;Tomasek;Nat Rev Mol Cell Biol,2002

5. Rho GTPases and cell migration;Ridley;J Cell Sci,2001

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