Cardiovascular safety of oral semaglutide in patients with type 2 diabetes: Rationale, design and patient baseline characteristics for the PIONEER 6 trial

Author:

Bain Stephen C.1ORCID,Mosenzon Ofri2,Arechavaleta Rosario3,Bogdański Pawel4,Comlekci Abdurrahman5,Consoli Agostino6,Deerochanawong Chaicharn7,Dungan Kathleen8ORCID,Faingold Maria C.9,Farkouh Michael E.10,Franco Denise R.11,Gram Jeppe12,Guja Cristian13ORCID,Joshi Pankaj14,Malek Rachid15,Merino-Torres Juan F.16,Nauck Michael A.17ORCID,Pedersen Sue D.18,Sheu Wayne H. -H.192021,Silver Robert J.22,Tack Cees J.23,Tandon Nikhil24,Jeppesen Ole K.25,Strange Mette25,Thomsen Mette25,Husain Mansoor1026

Affiliation:

1. Diabetes Research Unit Cymru; Swansea University Medical School; Swansea UK

2. Diabetes Unit, Division of Internal Medicine; Hadassah Hebrew University Hospital; Jerusalem Israel

3. Department of Endocrinology, Universidad Autonoma de Guadalajara; Jalisco Mexico

4. Department of Education and Obesity Treatment and Metabolic Disorders; Poznan University of Medical Sciences; Poznan Poland

5. Department of Endocrinology; Dokuz Eylul University Faculty of Medicine, Balcova; Izmir Turkey

6. Department of Medicine and Aging, and Center of Aging Science and Translational Medicine (CESI-Met); "G. d'Annunzio" University of Chieti-Pescara; Chieti Italy

7. Diabetes and Endocrinology Unit, Rajavithi Hospital; Rangsit Medical School; Bangkok Thailand

8. Division of Endocrinology, Diabetes and Metabolism; Ohio State University; Columbus Ohio

9. Department of Endocrinology and Metabolism; Dr Cesar Milstein Hospital; Buenos Aires Argentina

10. Peter Munk Cardiac Centre, University Health Network, Department of Medicine and the Heart and Stroke Richard Lewar Centre; University of Toronto; Toronto Ontario Canada

11. CPCLIN Clinical Research Center; São Paulo Brazil

12. Department of Endocrinology; Hospital of Southwest Denmark; Esbjerg Denmark

13. Department of Diabetes, Nutrition and Metabolic Diseases; University of Medicine and Pharmacy 'Carol Davila'; Bucharest Romania

14. Diabetes Care and Clinical Trials Centre; Pretoria South Africa

15. Department of Internal Medicine; CHU Sétif; Sétif Algeria

16. Department of Endocrinology and Nutrition; University Hospital La Fe; Valencia Spain

17. Diabetes Center Bochum-Hattingen, Medical Department I; St Josef-Hospital, Ruhr-University Bochum; Bochum Germany

18. C-ENDO Diabetes and Endocrinology Clinic; Calgary Alberta, Canada

19. Division of Endocrinology and Metabolism, Department of Internal Medicine; Taichung Veterans General Hospital; Taichung Taiwan

20. School of Medicine; National Yang-Ming University; Taipei Taiwan

21. School of Medicine; National Defense Medical Centre; Taipei Taiwan

22. Southern New Hampshire Diabetes and Endocrinology; Nashua New Hampshire

23. Department of Internal Medicine; Radboud University Medical Center; Nijmegen The Netherlands

24. Department of Endocrinology and Metabolism; All India Institute of Medical Sciences; New Delhi India

25. Novo Nordisk A/S; Bagsvaerd Denmark

26. Toronto General Hospital Research Institute, and the Ted Rogers Centre for Heart Research; Toronto Canada

Funder

Novo Nordisk

Publisher

Wiley

Subject

Endocrinology,Endocrinology, Diabetes and Metabolism,Internal Medicine

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