Airway remodelling rather than cellular infiltration characterizes both type2 cytokine biomarker‐high and ‐low severe asthma-Reference-Cited by-同舟云学术

Airway remodelling rather than cellular infiltration characterizes both type2 cytokine biomarker‐high and ‐low severe asthma

Published:2022-05-25 Issue:10 Volume:77 Page:2974-2986
ISSN:0105-4538
Container-title:Allergy
language:en
Short-container-title:Allergy

Author:

Khalfaoui Latifa¹,Symon Fiona A.¹,Couillard Simon²^ORCID,Hargadon Beverley¹,Chaudhuri Rekha³,Bicknell Steve³,Mansur Adel H.⁴^ORCID,Shrimanker Rahul²,Hinks Timothy S. C.²^ORCID,Pavord Ian D.²^ORCID,Fowler Stephen J.⁵^ORCID,Brown Vanessa⁶,McGarvey Lorcan P.⁶,Heaney Liam G.⁶^ORCID,Austin Cary D.⁷,Howarth Peter H.⁸,Arron Joseph R.⁷,Choy David F.⁷,Bradding Peter¹^ORCID

Affiliation:

1. Department of Respiratory Sciences, Leicester Respiratory NIHR BRC, Glenfield Hospital University of Leicester Leicester UK

2. NIHR Oxford Respiratory BRC, Nuffield Department of Medicine University of Oxford Oxford UK

3. Gartnavel General Hospital, Glasgow, and Institute of Infection, Immunity and Inflammation University of Glasgow Glasgow UK

4. University of Birmingham and Heartlands Hospital University Hospitals Birmingham NHS Foundation Trust Birmingham UK

5. School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre and NIHR Manchester Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust University of Manchester Manchester UK

6. Wellcome‐Wolfson‐ Centre for Experimental Medicine Queen's University Belfast School of Medicine Dentistry and Biomedical Sciences Belfast UK

7. Genentech, Inc. South San Francisco California USA

8. School of Clinical and Experimental Sciences, NIHR Southampton Biomedical Research Centre University of Southampton Southampton UK

Funder

Medical Research Council Canada

National Institute for Health Research

Manchester Biomedical Research Centre

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/all.15376

Reference68 articles.

1. Asthma: prevalence and cost of illness

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3. Proceedings of the ATS Workshop on Refractory Asthma

4. Pathological features and inhaled corticosteroid response of eosinophilic and non-eosinophilic asthma

5. A Large Subgroup of Mild-to-Moderate Asthma Is Persistently Noneosinophilic

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