JAK1/2 pathway inhibition suppresses M2 polarization and overcomes resistance of myeloma to lenalidomide by reducing TRIB1, MUC1, CD44, CXCL12, and CXCR4 expression
Author:
Affiliation:
1. Institute for Myeloma & Bone Cancer Research West Hollywood CA USA
2. Oncotherapeutics West Hollywood CA USA
Publisher
Wiley
Subject
Hematology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1111/bjh.16158
Reference43 articles.
1. Janus kinase inhibition by ruxolitinib extends dasatinib- and dexamethasone-induced remissions in a mouse model of Ph+ ALL
2. Macrophage Cytokines: Involvement in Immunity and Infectious Diseases
3. Macrophages in multiple myeloma: emerging concepts and therapeutic implications
4. WNT signaling in bone homeostasis and disease: from human mutations to treatments
5. Multiple myeloma cells recruit tumor-supportive macrophages through the CXCR4/CXCL12 axis and promote their polarization toward the M2 phenotype
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