GR113808: a novel, selective antagonist with high affinity at the 5-HT4 receptor

Author:

Gale J. D.,Grossman C. J.,Whitehead J. W. F.,Oxford A.W.,Bunce K. T.,Humphrey P. P. A.

Publisher

Wiley

Subject

Pharmacology

Reference23 articles.

1. Receptors for 5-hydroxytryptamine and noradrenaline in rabbit isolated ear artery and aorta;APPERLEY;Br. J. Pharmacol.,1976

2. 5-Hydroxytryptamine4 receptors mediate relaxation of the rat oesophageal tunica muscularis mucosae;BAXTER;Naunyn-Schmied. Arch. Pharmacol.,1991

3. Pharmacological characterization of 5-hydroxytryptamine4 (5-HT4) receptors positively coupled to adenylate cyclase in adult guinea-pig hippocampal membranes: Effect of substituted benzamide derivatives;BOCKAERT;Mol. Pharmacol.,1990

4. SDZ 205-557, a selective, surmountable antagonist for 5-HT4 receptors in the isolated guinea-pig ileum;BUCHHEIT;Naunyn-Schmied. Arch. Pharmacol.,1992

5. The gastrointestinal prokinetic benzamide derivatives are agonists at the non-classical 5-HT receptor (5-HT4) positively coupled to adenylate cyclase in neurones;DUMUIS;Naunyn-Schmied. Arch. Pharmacol.,1989

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