In vivo pharmacological characterization of the non-peptide endothelin receptor antagonist SB 209670

Author:

Douglas Stephen A.,Edwards Richard M.,Elliott John D.,Ohlstein Eliot H.

Publisher

Wiley

Subject

Pharmacology

Reference38 articles.

1. Discrimination between ETA- and ETB-receptor-mediated effects of endothelin-1 and [Ala1,3,11,15] endothelin-1 by BQ-123 in the anaesthetized rat;BIGAUD;Br. J. Pharmacol.,1992

2. Nonpeptide endothelin receptor antagonists. III: effect of SB 209670 and BQ-123 on acute renal failure in anesthetized dogs;BROOKS;J. Pharmacol. Exp. Ther.,1994

3. Pathophysiological role of endothelin revealed by the first orally active endothelin receptor antagonist;CLOZEL;Nature,1993a

4. In vivo pharmacology of Ro 46-2005, the first synthetic nonpeptide endothelin receptor antagonist: implications for endothelin physiology;CLOZEL;J. Cardiovasc. Pharmacol.,1993b

5. Design of a functional antagonist of endothelin;CODY;J. Med. Chem.,1992

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