The broad-spectrum anti-emetic activity of the novel non-peptide tachykinin NK1 receptor antagonist GR203040

Author:

Gardner C.J.,Twissell D.J.,Dale T.J.,Gale J.D.,Jordan C.C.,Kilpatrick G.J.,Bountra C.,Ward P.

Publisher

Wiley

Subject

Pharmacology

Reference23 articles.

1. The pharmacology of GR203040, a novel, potent and selective non-peptide tachykinin NK1 receptor antagonist;BEATTIE;Br. J. Pharmacol.,1995

2. Anti-emetic profile of a nonpeptide neurokinin NK1 receptor antagonist, CP-99,994, in ferrets;BOUNTRA;Eur. J. Pharmacol.,1993

3. Changes in serotonin metabolism in cancer patients: its relationship to nausea and vomiting induced by chemotherapeutic drugs;CUBEDDU;Br. J. Cancer,1992

4. Anti-emetic activity of neurokinin NK1 receptor antagonists is mediated centrally in the ferret;GARDNER;Br. J. Pharmacol.,1994

5. Evidence that the anti-emetic effects of NK1 receptor antagonists are centrally mediated;HARGREAVES;Can. J. Physiol. Pharmacol.,1994

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