Changes in aldehyde dehydrogenase 2 expression in rat blood vessels during glyceryl trinitrate tolerance development and reversal

Author:

D'Souza Y1,Dowlatshahi S1,Bennett BM

Affiliation:

1. Department of Pharmacology and Toxicology, Faculty of Health Sciences, Queen's University, Kingston, Ontario, Canada

Publisher

Wiley

Subject

Pharmacology

Reference52 articles.

1. Relationship between biotransformation of glyceryl trinitrate and cyclic GMP accumulation in various cultured cell lines;Bennett BM;J Pharmacol Exp Ther,1989

2. Hepatic cytochrome P450‐mediated activation of rat aortic guanylyl cyclase by glyceryl trinitrate;Bennett BM;J Pharmacol Exp Ther,1992

3. Bioactivation of Nitroglycerin by Purified Mitochondrial and Cytosolic Aldehyde Dehydrogenases

4. Partially Irreversible Inactivation of Mitochondrial Aldehyde Dehydrogenase by Nitroglycerin

5. Mechanism of glyceryl trinitrate‐induced vasodilation. I. Relationship between drug biotransformation, tissue cyclic GMP elevation and relaxation of rabbit aorta;Brien JF;J Pharmacol Exp Ther,1988

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