Myocardial pharmacokinetics of ebastine, a substrate for cytochrome P450 2J, in rat isolated heart-Reference-Cited by-同舟云学术

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Myocardial pharmacokinetics of ebastine, a substrate for cytochrome P450 2J, in rat isolated heart

Published:2011-07-25 Issue:8 Volume:163 Page:1733-1739
ISSN:0007-1188
Container-title:British Journal of Pharmacology
language:en
Short-container-title:

Author:

Kang W,Elitzer S,Noh K,Bednarek T,Weiss M

Publisher

Wiley

Subject

Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1476-5381.2011.01338.x/fullpdf

Reference20 articles.

1. Cytochrome P450 enzymes and the heart;Chaudhary;IUBMB Life,2009

2. Detection of human CYP2C8, CYP2C9, and CYP2J2 in cardiovascular tissues;DeLozier;Drug Metab Dispos,2007

3. Studies on the first-pass metabolism of ebastine in rats;Fujii;Arzneimittelforschung,1997

4. Involvement of CYP2J2 and CYP4F12 in the metabolism of ebastine in human intestinal microsomes;Hashizume;J Pharmacol Exp Ther,2002

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1. Cardiomyocyte-specific CYP2J2 and its therapeutic implications;Expert Opinion on Drug Metabolism & Toxicology;2022-08-03

2. Lipid composition and macromolecular crowding effects on CYP2J2‐mediated drug metabolism in nanodiscs;Protein Science;2019-04

3. Cytochrome P450 2J2: Potential Role in Drug Metabolism and Cardiotoxicity;Drug Metabolism and Disposition;2018-04-25

4. Functional characterization of drug uptake and metabolism in the heart;Expert Opinion on Drug Metabolism & Toxicology;2011-08-26

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