2‐(4‐(Biphenyl‐4‐ylamino)‐6‐chloropyrimidin‐2‐ylthio)octanoic acid (HZ52) – a novel type of 5‐lipoxygenase inhibitor with favourable molecular pharmacology and efficacyin vivo-Reference-Cited by-同舟云学术

2‐(4‐(Biphenyl‐4‐ylamino)‐6‐chloropyrimidin‐2‐ylthio)octanoic acid (HZ52) – a novel type of 5‐lipoxygenase inhibitor with favourable molecular pharmacology and efficacyin vivo

Published:2011-08-28 Issue:2b Volume:164 Page:781-793
ISSN:0007-1188
Container-title:British Journal of Pharmacology
language:en
Short-container-title:British Journal of Pharmacology

Author:

Greiner C¹,Hörnig C²,Rossi A³,Pergola C⁴,Zettl H²,Schubert‐Zsilavecz M²,Steinhilber D²,Sautebin L³,Werz O¹⁴

Affiliation:

1. Universität Tuebingen, Pharmazeutisches Institut, Tuebingen, Germany

2. Johann Wolfgang Goethe‐Universität, Institut für Pharmazeutische Chemie/ZAFES/LIFF/OSF, Frankfurt am Main, Germany

3. Department of Experimental Pharmacology, University of Naples Federico II, Naples, Italy

4. Institute of Pharmacy, Friedrich‐Schiller‐University Jena, Jena, Germany

Publisher

Wiley

Subject

Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1476-5381.2011.01451.x

Reference36 articles.

1. Kinetic mechanism of guinea pig neutrophil 5‐lipoxygenase;Aharony D;J Biol Chem,1986

2. Inhibitors of the 5-Lipoxygenase Pathway in Atherosclerosis

3. Antioxidant Determinations by the Use of a Stable Free Radical

4. Pharmacology of MK-0591 (3-[1-(4-chlorobenzyl)-3-(t-butylthio)-5-(quinolin-2-yl-methoxy)-indol-2-yl]-2,2-dimethyl propanoic acid), a potent, orally active leukotriene biosynthesis inhibitor

5. Cell type-dependent activation of 5-lipoxygenase by arachidonic acid

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