Detrimental effects of melanocortin-1 receptor (MC1R) variants on the clinical outcomes of BRAF V600 metastatic melanoma patients treated with BRAF inhibitors-Reference-Cited by-同舟云学术

Detrimental effects of melanocortin-1 receptor (MC1R) variants on the clinical outcomes of BRAF V600 metastatic melanoma patients treated with BRAF inhibitors

Published:2016-11 Issue:6 Volume:29 Page:679-687
ISSN:1755-1471
Container-title:Pigment Cell & Melanoma Research
language:en
Short-container-title:Pigment Cell Melanoma Res.

Author:

Guida Michele¹,Strippoli Sabino¹,Ferretta Anna¹²,Bartolomeo Nicola³,Porcelli Letizia⁴,Maida Immacolata²,Azzariti Amalia⁴,Tommasi Stefania⁵,Grieco Claudia²,Guida Stefania⁶,Albano Anna¹,Lorusso Vito¹,Guida Gabriella²

Affiliation:

1. Medical Oncology Department; National Cancer Research Centre ‘Giovanni Paolo II’; Bari Italy

2. Department of Basic Medical Sciences, Neurosciences and Sense Organs; University of Bari; Bari Italy

3. Department of Biomedical Sciences and Human Oncology; University of Bari; Bari Italy

4. Experimental Pharmacology Laboratory; National Cancer Research Centre ‘Giovanni Paolo II’; Bari Italy

5. Molecular Genetics Laboratory and Radiology; National Cancer Research Centre ‘Giovanni Paolo II’; Bari Italy

6. Dermatology Unit; University of Modena and Reggio Emilia; Modena Italy

Funder

Maria Ruggieri Association

Italian Melanoma Intergroup

Publisher

Wiley

Subject

Dermatology,General Biochemistry, Genetics and Molecular Biology,Oncology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/pcmr.12516/fullpdf

Reference52 articles.

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3. alpha-Melanocyte-stimulating hormone protects from ultraviolet radiation-induced apoptosis and DNA damage;Böhm;J. Biol. Chem.,2005

4. Complete loss of PTEN protein expression correlates with shorter time to brain metastasis and survival in stage IIIB/C melanoma patients with BRAFV600 mutations;Bucheit;Clin. Cancer Res.,2014

5. MC1R is a potent regulator of PTEN after UV exposure in melanocytes;Cao;Mol. Cell,2013

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