Human B-Cell Clones Expressing Lupus Nephritis-Associated Anti-DNA Idiotypes are Preferentially Expanded without Somatic Mutation
Author:
Publisher
Wiley
Subject
Immunology,General Medicine
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1365-3083.1993.tb02569.x/fullpdf
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1. The complete nucleotide sequences of the heavy chain variable regions of six monospecific rheumatoid factors derived from Epstein-Barr virus-transformed B cells isolated from the synovial tissue of patients with rheumatoid arthritis. Further evidence that some autoantibodies are unmutated copies of germ line genes.
2. A novel class of anti-DNA antibodies identified in BALB/c mice.
3. Molecular characterization of a somatically mutated anti-DNA antibody bearing two systemic lupus erythematosus-related idiotypes.
4. Somatic mutations in the variable regions of a human IgG anti-double-stranded DNA autoantibody suggest a role for antigen in the induction of systemic lupus erythematosus.
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1. Dual Recognition of Lipid A and DNA by Human Antibodies Encoded by the VH4-21 Gene A Possible Link between Infection and Lupusa;Annals of the New York Academy of Sciences;2008-06-28
2. Systematic analysis of sequences of anti-DNA antibodies—relevance to theories of origin and pathogenicity;Lupus;2002-12
3. Chemically Modified Ribozyme to V Gene Inhibits Anti-DNA Production and the Formation of Immune Deposits Caused by Lupus Lymphocytes;The Journal of Immunology;2000-11-15
4. Isolation, Characterization and Sequence Analysis of Five IgG Monoclonal Anti-β2-Glycoprotein-1 and Anti-Prothrombin Antigen-Binding Fragments Generated by Phage Display;The Journal of Immunology;1999-10-15
5. Isolation of Human Anti-branched Chain α-Oxo Acid Dehydrogenase-E2 Recombinant Antibodies by Ig Repertoire Cloning in Idiopathic Dilated Cardiomyopathy;Molecules and Cells;1999-02
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