Epidermal Pyridoxal 5′-Phosphate Depletion, Inhibition of DNA Synthesis, and Inhibition of the Expression of Ornithine Decarboxylase Activity by the Vitamin B-6 Antagonist 4′-Deoxypyridoxine

Author:

Connor Michael J.,Lowe Nicholas J.

Publisher

Elsevier BV

Subject

Cell Biology,Dermatology,Molecular Biology,Biochemistry

Reference26 articles.

1. Induction of the polyamine biosynthesis enzymes in mouse epidermis and their specificity for tumor promotion;O'Brien;Cancer Res,1975

2. Amine synthesis in rapidly growing tissues: ornithine decarboxylase activity in regenerating rat liver, chick embryo, and various tumors;Russell;Proc Natl Acad Sci USA,1968

3. Ornithine decarboxylase activity, cell proliferation, and tumor promotion in mouse epidermis in vivo;Marks;Cancer Res,1979

4. Effects of 12-o-tetradecanoylphorbol-13-acetate and mezerein on epidermal ornithine decarboxylase activity, isoproterenol-stimulated levels of cyclic adenosine 3'5'-monophosphate, and induction of mouse skin tumors in vivo;Mufson;Cancer Res,1979

5. Alpha-difluoromethyl-ornithine, an irreversible inhibitor of ornithine decarboxylase, inhibits tumor promoter-induced polyamine accumulation and carcinogenesis in mouse skin;Weeks;Proc Natl Acad Sci USA,1982

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