A semi-mechanistic absorption model to evaluate drug-drug interaction with dabigatran: application with clarithromycin-Reference-Cited by-同舟云学术

A semi-mechanistic absorption model to evaluate drug-drug interaction with dabigatran: application with clarithromycin

Published:2013-06-20 Issue:1 Volume:76 Page:107-113
ISSN:0306-5251
Container-title:British Journal of Clinical Pharmacology
language:en
Short-container-title:Br J Clin Pharmacol

Author:

Delavenne Xavier,Ollier Edouard,Basset Thierry,Bertoletti Laurent,Accassat Sandrine¹,Garcin Arnauld²,Laporte Silvy,Zufferey Paul,Mismetti Patrick

Affiliation:

1. Service de Médecine Thérapeutique; CHU de Saint-Etienne; F-42055; Saint-Etienne

2. Déperpartement d'anesthésie Réanimation; CHU de Saint-Etienne; F-42055; Saint-Etienne

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/bcp.12055/fullpdf

Reference19 articles.

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2. Dabigatran versus warfarin in patients with atrial fibrillation;Connolly;N Engl J Med,2009

3. The metabolism and disposition of the oral direct thrombin inhibitor, dabigatran, in humans;Blech;Drug Metab Dispos,2008

4. Pharmacokinetic profile of the oral direct thrombin inhibitor dabigatran etexilate in healthy volunteers and patients undergoing total hip replacement;Stangier;J Clin Pharmacol,2005

5. CHMP Pradaxa, INN- dabigatran etexilate CHMP assessment report for radaxa 2008 1 36 http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Public_assessment_report/human/000829/WC500041062.pdf

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