A Promoter Polymorphism in theCD59Complement Regulatory Protein Gene in Donor Lungs Correlates With a Higher Risk for Chronic Rejection After Lung Transplantation

Author:

Budding K.1,van de Graaf E. A.2,Kardol-Hoefnagel T.1,Broen J. C. A.13,Kwakkel-van Erp J. M.2,Oudijk E.-J. D.4,van Kessel D. A.4,Hack C. E.13,Otten H. G.1

Affiliation:

1. Laboratory of Translational Immunology; University Medical Center Utrecht; Utrecht The Netherlands

2. Department of Respiratory Medicine; University Medical Center Utrecht; Utrecht The Netherlands

3. Departments of Rheumatology and Dermatology; University Medical Center Utrecht; Utrecht The Netherlands

4. Center of Interstitial Lung Diseases; St. Antonius Hospital; Nieuwegein The Netherlands

Funder

Research Fund of the Department of Pulmonary Diseases

Publisher

Wiley

Subject

Pharmacology (medical),Transplantation,Immunology and Allergy

Reference30 articles.

1. The role of complement in the early immune response to transplantation;Sacks;Nat Rev Immunol,2012

2. Structure of the CD59-encoding gene: Further evidence of a relationship to murine lymphocyte antigen ly-6 protein;Petranka;Proc Natl Acad Sci U S A,1992

3. Gene structure of human CD59 and demonstration that discrete mRNAs are generated by alternative polyadenylation;Tone;J Mol Biol,1992

4. Analysis of the gene that encodes the complement regulatory protein, membrane inhibitor of reactive lysis (CD59). Identification of an alternatively spliced exon and characterization of the transcriptional regulatory regions of the promoter;Holguin;J Immunol,1996

5. High level transcription of the complement regulatory protein CD59 requires an enhancer located in intron 1;Tone;J Biol Chem,1999

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3