Comparison of dual‐plane micro‐drop injection of botulinum toxin type A with two traditional methods for treating hypertrophic scars in the tension zone: A long‐term clinical application study

Author:

Jiang Banghong1,Zhang Jianting2,Yang Wenjian2,Wang Yukun1,Huang Sutao2,Qiu Jingjing2,Bian Bingzhi2,Zhang Li1,Zu Wenxuan3ORCID

Affiliation:

1. Department of Plastic Surgery 1st Affiliated Hospital of Bengbu Medical College Bengbu Anhui province China

2. Bengbu Medical College Bengbu Anhui province China

3. Department of Anatomy Bengbu Medical College Bengbu Anhui China

Abstract

AbstractBackgroundPatients with hypertrophic scarring tend to experience recurrence after treatment, which often occurs in areas of the body with high skin tension.AimsTo evaluate better treatments aimed at reducing the risk of scar recurrence in areas of high skin tension.MethodsPatients were randomly divided into the following three treatment groups: botulinum toxin type A (BTA) via dual‐plane micro‐drop injections, triamcinolone acetonide (TAC) suspension, and CO2 via fractional CO2 laser. Interventions were implemented in all three groups once a month for three consecutive sessions. After the final treatment, scarring was evaluated at 1, 3, 6, 12, and 24 months using the Patient and Observer Scar Assessment Scale (POSAS).ResultsThe 3‐month POSAS score for each scar indicator in the treatment groups was significantly lower than that in the preoperative groups (p < 0.001). The scar score in the TAC group decreased at 3 months and increased thereafter. For other groups, the scar score continually decreased at all time points according to the Patient Scar Assessment Scale. Based on the Observer Scar Assessment Scale, the scar score continuously decreased at all time points in the BTA group; in the TAC group, it decreased at 1 month and increased thereafter; and in the CO2 group, the scar score decreased at 3 months and subsequently stabilized.ConclusionsAll three treatment methods were effective. However, the BTA group experienced a reduced risk of scar recurrence and maintained long‐term treatment effects.

Funder

National College Students Innovation and Entrepreneurship Training Program

University Natural Science Research Project of Anhui Province

Publisher

Wiley

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