Fusobacterium nucleatuminfection of gingival epithelial cells leads to NLRP3 inflammasome-dependent secretion of IL-1β and the danger signals ASC and HMGB1

Author:

Bui Fiona Q.1,Johnson Larry12,Roberts JoAnn3,Hung Shu-Chen1,Lee Jungnam3,Atanasova Kalina Rosenova3,Huang Pei-Rong4,Yilmaz Özlem3,Ojcius David M.1

Affiliation:

1. Department of Biomedical Sciences; University of the Pacific, Arthur Dugoni School of Dentistry; San Francisco CA 95343 USA

2. Immunobiology Program; Instituto de Biofísica Carlos Chagas Filho, Federal University of Rio de Janeiro; Rio de Janeiro 21941 Brazil

3. Department of Periodontology and Emerging Pathogens Institute; University of Florida; Gainesville FL 32610 USA

4. Center for Molecular and Clinical Immunology; Chang Gung University; Gueishan Taoyuan 333 Taiwan

Funder

intramural funds from the University of the Pacific, NIDCR

Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro

Publisher

Hindawi Limited

Subject

Virology,Immunology,Microbiology

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