The quality of diagnostic guidelines for children in primary care: A meta‐epidemiological study

Author:

Thomas Elizabeth T1ORCID,Thomas Sarah T2ORCID,Perera Rafael3ORCID,Gill Peter J345ORCID,Moloney Susan678ORCID,Heneghan Carl1ORCID

Affiliation:

1. Centre for Evidence‐Based Medicine, Nuffield Department of Primary Care Health Sciences University of Oxford Oxford United Kingdom

2. Department of Neurology Gold Coast University Hospital Gold Coast Queensland Australia

3. Nuffield Department of Primary Care Health Sciences University of Oxford Oxford United Kingdom

4. Department of Paediatrics, Faculty of Medicine University of Toronto Toronto Ontario Canada

5. Hospital for Sick Children Toronto Ontario Canada

6. Department of Paediatrics Gold Coast University Hospital Gold Coast Queensland Australia

7. School of Medicine Griffith University Gold Coast Queensland Australia

8. Faculty of Health Sciences and Medicine Bond University Gold Coast Queensland Australia

Abstract

AimTo determine the quality of paediatric guidelines relevant to diagnosis of three of the most common conditions in primary care: fever, gastroenteritis and constipation.MethodsWe undertook a meta‐epidemiological study of paediatric guidelines for fever, gastroenteritis and gastroenteritis. We systematically searched MEDLINE, Embase, Trip Database, Guidelines International Network, the National Guideline Clearinghouse and WHO from February 2011 to September 2022 for guidelines from high‐income settings containing diagnostic recommendations. We assessed the quality of guideline reporting for included guidelines using the AGREE II tool.ResultsWe included 16 guidelines: fever (n = 7); constipation (n = 4) and gastroenteritis (n = 5). The overall quality across the three conditions was graded moderate (median AGREE II score 4.5/7, range 2.5–6.5) with constipation guidelines rated the highest (median 6/7), and fever rated the lowest (median 3.8/7). Major methodological weaknesses included consideration of guideline applicability. Half of the guidelines did not report involving parent representatives, and 56% did not adequately declare or address their competing interests.ConclusionsSubstantial variations exist in the quality of paediatric guidelines related to the diagnosis of primary care presentations. Better quality guidance is needed for general practitioners to improve diagnosis for children in primary care.

Publisher

Wiley

Subject

Pediatrics, Perinatology and Child Health

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