Unaccounted for regression to the mean renders conclusion of article titled “Uric acid lowering in relation to HbA1c reductions with the SGLT2 inhibitor tofogliflozin” unsubstantiated

Author:

Kahathuduwa Chanaka N.12ORCID,Thomas Diana M.3,Siu Cynthia4,Allison David B.5

Affiliation:

1. Department of Human Development and Family Studies; Texas Tech University; Lubbock Texas

2. Department of Physiology, Faculty of Medicine; University of Peradeniya; Peradeniya Sri Lanka

3. Department of Mathematics; US Military Academy; West Point New York

4. COS & Associates Ltd; Central Hong Kong

5. Department of Epidemiology and Biostatistics, School of Public Health - Bloomington; Indiana University; Bloomington Indiana

Funder

National Institutes of Health

Publisher

Wiley

Subject

Endocrinology,Endocrinology, Diabetes and Metabolism,Internal Medicine

Reference14 articles.

1. Uric acid lowering in relation to HbA1c reductions with the SGLT2 inhibitor tofogliflozin;Ouchi;Diabetes Obes Metab,2018

2. Regression towards mediocrity in hereditary stature;Galton;J Anthropol Inst Great Br Ir,1886

3. Common scientific and statistical errors in obesity research;George;Obesity (Silver Spring),2016

4. Regression to the mean: a commonly overlooked and misunderstood factor leading to unjustified conclusions in pediatric obesity research;Cockrell Skinner;Child Obes,2016

5. Ignoring regression to the mean leads to unsupported conclusion about obesity;Skinner;Int J Behav Nutr Phys Act,2015

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