Characterization of cytochrome P450 (CYP) 2D6 drugs as substrates of human organic cation transporters and multidrug and toxin extrusion proteins-Reference-Cited by-同舟云学术

Characterization of cytochrome P450 (CYP) 2D6 drugs as substrates of human organic cation transporters and multidrug and toxin extrusion proteins

Published:2021-02-23 Issue:6 Volume:178 Page:1459-1474
ISSN:0007-1188
Container-title:British Journal of Pharmacology
language:en
Short-container-title:Br J Pharmacol

Author:

Neul Claudia¹²,Hofmann Ute¹²,Schaeffeler Elke¹²³,Winter Stefan¹²,Klein Kathrin¹²,Giacomini Kathleen M.⁴⁵,Eichelbaum Michel¹²,Schwab Matthias¹²³⁶,Nies Anne T.¹²³^ORCID

Affiliation:

1. Dr. Margarete Fischer‐Bosch Institute of Clinical Pharmacology Stuttgart Germany

2. University of Tuebingen Tuebingen Germany

3. Cluster of Excellence iFIT (EXC2180) “Image‐Guided and Functionally Instructed Tumor Therapies” University of Tuebingen Tuebingen Germany

4. Department of Bioengineering and Therapeutic Sciences University of California San Francisco California USA

5. Institute of Human Genetics University of California San Francisco California USA

6. Departments of Clinical Pharmacology, Pharmacy and Biochemistry University of Tuebingen Tuebingen Germany

Funder

Deutsche Forschungsgemeinschaft

Publisher

Wiley

Subject

Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/bph.15370

Reference65 articles.

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3. Goals and practicalities of immunoblotting and immunohistochemistry: A guide for submission to the British Journal of Pharmacology

4. Correlation of CYP2D6 genotype with perhexiline phenotypic metabolizer status

5. In Vitro Methods to Support Transporter Evaluation in Drug Discovery and Development

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