Characterization of cytochrome P450 (CYP) 2D6 drugs as substrates of human organic cation transporters and multidrug and toxin extrusion proteins

Author:

Neul Claudia12,Hofmann Ute12,Schaeffeler Elke123,Winter Stefan12,Klein Kathrin12,Giacomini Kathleen M.45,Eichelbaum Michel12,Schwab Matthias1236,Nies Anne T.123ORCID

Affiliation:

1. Dr. Margarete Fischer‐Bosch Institute of Clinical Pharmacology Stuttgart Germany

2. University of Tuebingen Tuebingen Germany

3. Cluster of Excellence iFIT (EXC2180) “Image‐Guided and Functionally Instructed Tumor Therapies” University of Tuebingen Tuebingen Germany

4. Department of Bioengineering and Therapeutic Sciences University of California San Francisco California USA

5. Institute of Human Genetics University of California San Francisco California USA

6. Departments of Clinical Pharmacology, Pharmacy and Biochemistry University of Tuebingen Tuebingen Germany

Funder

Deutsche Forschungsgemeinschaft

Publisher

Wiley

Subject

Pharmacology

Reference65 articles.

1. The Concise Guide to PHARMACOLOGY 2019/20;Alexander S. P. H.;British Journal of Pharmacology,2019

2. The Concise Guide to PHARMACOLOGY 2019/20: Transporters;Alexander S. P. H.;British Journal of Pharmacology,2019

3. Goals and practicalities of immunoblotting and immunohistochemistry: A guide for submission to the British Journal of Pharmacology

4. Correlation of CYP2D6 genotype with perhexiline phenotypic metabolizer status

5. In Vitro Methods to Support Transporter Evaluation in Drug Discovery and Development

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