Translational issues for mitoprotective agents as adjunct to reperfusion therapy in patients with ST‐segment elevation myocardial infarction

Author:

Bøtker Hans Erik1ORCID,Cabrera‐Fuentes Hector Alejandro23456,Ruiz‐Meana Marisol78,Heusch Gerd9,Ovize Michel10

Affiliation:

1. Department of Cardiology Aarhus University Hospital Aarhus N Denmark

2. SingHealth Duke‐NUS Cardiovascular Sciences Academic Clinical Programme and Cardiovascular and Metabolic Disorders Program Duke‐National University of Singapore Medical School Singapore Singapore

3. National Heart Research Institute Singapore National Heart Centre Singapore Singapore

4. Institute of Biochemistry Medical School Justus‐Liebig University Giessen Germany

5. Tecnologico de Monterrey Centro de Biotecnologia‐FEMSA Monterrey Mexico

6. Institute of Fundamental Medicine and Biology Kazan (Volga Region) Federal University Kazan Russian Federation

7. Vall d'Hebron Institut de Recerca University Hospital Vall d'Hebron‐Universitat Autònoma Barcelona Spain

8. Centro de Investigación Biomédica en Red‐CV CIBER‐CV Spain

9. Institute for Pathophysiology West German Heart and Vascular Center University of Essen. Medical School Essen Germany

10. CarMeN Laboratory Hôpital Louis Pradel Hospices Civils de Lyon Université de Lyon and Explorations Fonctionnelles Cardiovasculaires INSERM U1060 Lyon France

Funder

Singapore Heart Foundation

Deutsche Forschungsgemeinschaft

Novo Nordisk Foundation Center for Basic Metabolic Research

Publisher

Wiley

Subject

Cell Biology,Molecular Medicine

Reference129 articles.

1. Improved outcomes in patients with ST-elevation myocardial infarction during the last 20 years are related to implementation of evidence-based treatments: experiences from the SWEDEHEART registry 1995–2014

2. National Trends in Heart Failure Hospitalization After Acute Myocardial Infarction for Medicare Beneficiaries

3. The pathophysiology of acute myocardial infarction and strategies of protection beyond reperfusion: a continual challenge;Heusch G;Eur Heart J,2017

4. Targeting reperfusion injury in patients with ST‐segment elevation myocardial infarction: trials and tribulations;Hausenloy DJ;Eur Heart J,2017

5. Mitochondrial non-specific pores remain closed during cardiac ischaemia, but open upon reperfusion

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