CD4:CD8 ratio in children with perinatally acquired HIV-1 infection
Author:
Affiliation:
1. Faculty of Medicine; Imperial College London; London UK
2. Imperial College Healthcare NHS Trust; London UK
Funder
Medical Research Council
National Institute for Health Research
Publisher
Wiley
Subject
Pharmacology (medical),Infectious Diseases,Health Policy
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/hiv.12642/fullpdf
Reference22 articles.
1. Paediatric European Network for Treatment of AIDS Treatment Guidelines 2016 update: antiretroviral therapy recommended for all children living with HIV;Foster;HIV Med,2017
2. UNAids UNAIDS Fact Sheet 2016 2016 http://www.unaids.org/sites/default/files/media_asset/UNAIDS_FactSheet_en.pdf
3. HIV-infected individuals with low CD4/CD8 ratio despite effective antiretroviral therapy exhibit altered T cell subsets, heightened CD8+ T cell activation, and increased risk of non-AIDS morbidity and mortality;Serrano-Villar;PLoS Pathog,2014
4. Increased risk of serious Non-AIDS-related events in HIV-infected subjects on antiretroviral therapy associated with a low CD4/CD8 Ratio;Serrano-Villar;PLoS One,2014
5. The CD4/CD8 ratio as a marker T-cell activation, senescence and activation/exhaustion in treated HIV-infected children and young adults;Sainz;AIDS,2013
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