Affiliation:
1. Perelman School of Medicine University of Pennsylvania Philadelphia Pennsylvania USA
2. Section of Pediatric Dermatology Children's Hospital of Philadelphia Philadelphia Pennsylvania USA
3. Department of Dermatology University of Pennsylvania Philadelphia Pennsylvania USA
4. Department of Pathology and Laboratory Medicine Children's Hospital of Philadelphia Philadelphia Pennsylvania USA
Abstract
AbstractHenoch Schönlein purpura (HSP), also known as IgA vasculitis, is a systemic small‐vessel vasculitis typically occurring in children 3–15 years of age, with peak incidence at 4–6 years. It is characterized by a constellation of symptoms including palpable purpura, arthralgias or arthritis, abdominal pain including intussusception, and renal involvement. We report a patient with these clinical findings whose IgA immunofluorescence was negative but with a presumptive diagnosis of HSP at 16 months of age, significantly younger than the classic population. This condition rarely affects this age group, and we highlight the importance of considering vasculitis in children of all ages, as a failure to diagnose could lead to insufficient long‐term monitoring, particularly regarding renal function.