Targeted deletion of GD3 synthase protects against MPTP-induced neurodegeneration

Author:

Akkhawattanangkul Y.1,Maiti P.2,Xue Y.2,Aryal D.345,Wetsel W. C.345,Hamilton D.1,Fowler S. C.6,McDonald M. P.27ORCID

Affiliation:

1. Department of Comparative Medicine; University of Tennessee Health Science Center; Memphis TN USA

2. Department of Neurology; University of Tennessee Health Science Center; Memphis TN USA

3. Department of Psychiatry & Behavioral Sciences; Duke University Medical Center; Durham NC USA

4. Department of Cell Biology; Duke University Medical Center; Durham NC USA

5. Department of Neurobiology; Duke University Medical Center; Durham NC USA

6. Department of Pharmacology & Toxicology; University of Kansas; Lawrence KS USA

7. Department of Anatomy & Neurobiology; University of Tennessee Health Science Center; Memphis TN USA

Funder

Michael J. Fox Foundation for Parkinson's Research

National Institute of Neurological Disorders and Stroke

National Institute of Child Health and Development

Publisher

Wiley

Subject

Behavioral Neuroscience,Neurology,Genetics

Reference106 articles.

1. Altered ceramide acyl chain length and ceramide synthase gene expression in Parkinson's disease;Abbott;Mov Disord,2014

2. Gait dynamics in mouse models of Parkinson's disease and Huntington's disease;Amende;J Neuroeng Rehabil,2005

3. Apoptosis and autophagy in nigral neurons of patients with Parkinson's disease;Anglade;Histol Histopathol,1997

4. Sex differences in motor behavior in the MPTP mouse model of Parkinson's disease;Antzoulatos;Pharmacol Biochem Behav,2010

5. Role of sphingolipid-mediated cell death in neurodegenerative diseases;Ariga;J Lipid Res,1998

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