Cytomegalovirus serological screening at the first antenatal visit: A tertiary‐centre audit of general practitioner practices and maternal seroprevalence

Author:

Rudd Ignatius Patrick1ORCID,Marzan Melvin Barrientos123ORCID,Hui Lisa123ORCID

Affiliation:

1. Department of Perinatal Medicine Mercy Hospital for Women Heidelberg Victoria Australia

2. Department of Obstetrics and Gynaecology University of Melbourne Parkville Victoria Australia

3. Reproductive Epidemiology Group Murdoch Children's Research Institute Parkville Victoria Australia

Abstract

Little is published on cytomegalovirus (CMV) serological screening at the first antenatal visit or the contemporary CMV seroprevalence rates among the Australian pregnant population. We performed a retrospective analysis of public hospital births in a major tertiary centre (n = 840) over a two month period. We found that 13.6% (95% confidence interval (CI) 11.4–16.1%) of women had been screened for CMV at their first antenatal visit with their general practitioner. Of these, 43.0% (95% CI 34.3–52.1%) were CMV seronegative and therefore susceptible to primary infection. Seronegative women were also more likely to have been born in an economically developed country, to live in a socio‐economically advantaged postcode and to be nulliparous. The information from this study may help guide future studies of congenital CMV risk reduction strategies.

Funder

Norman Beischer Medical Research Foundation

Publisher

Wiley

Subject

Obstetrics and Gynecology,General Medicine

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