European Neuroendocrine Tumour Society (ENETS) 2023 guidance paper for nonfunctioning pancreatic neuroendocrine tumours

Author:

Kos‐Kudła Beata1ORCID,Castaño Justo P.2ORCID,Denecke Timm3,Grande Enrique4,Kjaer Andreas5,Koumarianou Anna6ORCID,de Mestier Louis7ORCID,Partelli Stefano8,Perren Aurel9,Stättner Stefan10,Valle Juan W.1112,Fazio Nicola13

Affiliation:

1. Department of Endocrinology and Neuroendocrine Tumours, Department of Pathophysiology and Endocrinology Medical University of Silesia Katowice Poland

2. Maimonides Biomedical Research Institute of Córdoba, University of Córdoba, Hospital Universitario Reina Sofía, Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición, (CIBERobn) Córdoba Spain

3. Department of Diagnostic and Interventional Radiology University Medical Centre Leipzig Leipzig Germany

4. Medical Oncology Department MD Anderson Cancer Centre Madrid Madrid Spain

5. Department of Clinical Physiology and Nuclear Medicine and Cluster for Molecular Imaging Copenhagen University Hospital – Righospitalet and Department of Biomedical Sciences, University of Copenhagen Copenhagen Denmark

6. Hematology Oncology Unit, Fourth Department of Internal Medicine Attikon University Hospital, National and Kapodistrian University of Athens Athens Greece

7. Université Paris‐Cité, Department of Pancreatology and Digestive Oncology Beaujon Hospital (APHP.Nord) and INSERM U1149 Paris France

8. Pancreatic Translational and Clinical Research Centre, Pancreatic and Transplant Surgery Unit Vita‐Salute San Raffaele University Milan Italy

9. Institute of Pathology University of Bern Bern Switzerland

10. Department of General, Visceral and Vascular Surgery Salzkammergut Klinikum, OÖG Vöcklabruck Austria

11. Division of Cancer Sciences University of Manchester Manchester UK

12. Department of Medical Oncology The Christie NHS Foundation Trust Manchester UK

13. Division of Gastrointestinal Medical Oncology and Neuroendocrine Tumours European Institute of Oncology (IEO), IRCCS Milan Italy

Abstract

AbstractThis ENETS guidance paper for well‐differentiated nonfunctioning pancreatic neuroendocrine tumours (NF‐Pan‐NET) has been developed by a multidisciplinary working group, and provides up‐to‐date and practical advice on the management of these tumours. Using the extensive experience of centres treating patients with NF‐Pan‐NEN, the authors of this guidance paper discuss 10 troublesome questions in everyday clinical practice. Our many years of experience in this field are still being verified in the light of the results of new clinical, which set new ways of proceeding in NEN. The treatment of NF‐Pan‐NEN still requires a decision of a multidisciplinary team of specialists in the field of neuroendocrine neoplasms.

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Endocrine and Autonomic Systems,Endocrinology,Endocrinology, Diabetes and Metabolism

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