Nanomaterial strategies in wound healing: A comprehensive review of nanoparticles, nanofibres and nanosheets

Author:

Afshar Mohammad12,Rezaei Alireza3,Eghbali Samira45,Nasirizadeh Samira56,Alemzadeh Effat7,Alemzadeh Esmat8,Shadi Mehri1,Sedighi Mahsa56

Affiliation:

1. Department of Anatomy, Faculty of Medicine Birjand University of Medical Sciences Birjand Iran

2. Medical Toxicology Research Center Mashhad University of Medical Sciences Mashhad Iran

3. Anatomical Clinical Pathologist Islamic Azad University of Medical Sciences Mashhad Iran

4. Department of Pharmacognosy and Traditional Pharmacy School of Pharmacy, Birjand University of Medical Sciences Birjand Iran

5. Cellular and Molecular Research Center Birjand University of Medical Sciences Birjand Iran

6. Department of Pharmaceutics and Nanotechnology School of Pharmacy, Birjand university of Medical Sciences Birjand Iran

7. Infectious Diseases Research Center Birjand University of Medical Sciences Birjand Iran

8. Department of Medical Biotechnology Faculty of Medicine, Birjand University of Medical Sciences Birjand Iran

Abstract

AbstractWound healing is a complex process that orchestrates the coordinated action of various cells, cytokines and growth factors. Nanotechnology offers exciting new possibilities for enhancing the healing process by providing novel materials and approaches to deliver bioactive molecules to the wound site. This article elucidates recent advancements in utilizing nanoparticles, nanofibres and nanosheets for wound healing. It comprehensively discusses the advantages and limitations of each of these materials, as well as their potential applications in various types of wounds. Each of these materials, despite sharing common properties, can exhibit distinct practical characteristics that render them particularly valuable for healing various types of wounds. In this review, our primary focus is to provide a comprehensive overview of the current state‐of‐the‐art in applying nanoparticles, nanofibres, nanosheets and their combinations to wound healing, serving as a valuable resource to guide researchers in their appropriate utilization of these nanomaterials in wound‐healing research. Further studies are necessary to gain insight into the application of this type of nanomaterials in clinical settings.

Publisher

Wiley

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