A Novel, Blocking, Fc-Silent Anti-CD40 Monoclonal Antibody Prolongs Nonhuman Primate Renal Allograft Survival in the Absence of B Cell Depletion-Reference-Cited by-同舟云学术

A Novel, Blocking, Fc-Silent Anti-CD40 Monoclonal Antibody Prolongs Nonhuman Primate Renal Allograft Survival in the Absence of B Cell Depletion

Published:2015-07-02 Issue:11 Volume:15 Page:2825-2836
ISSN:1600-6135
Container-title:American Journal of Transplantation
language:en
Short-container-title:

Author:

Cordoba F.¹,Wieczorek G.¹,Audet M.²,Roth L.¹,Schneider M. A.¹,Kunkler A.¹,Stuber N.³,Erard M.¹,Ceci M.¹,Baumgartner R.³,Apolloni R.¹,Cattini A.⁴,Robert G.¹,Ristig D.¹,Munz J.¹,Haeberli L.¹,Grau R.⁵,Sickert D.⁶,Heusser C.¹,Espie P.⁶,Bruns C.¹,Patel D.¹,Rush J. S.¹

Affiliation:

1. Department of Autoimmunity, Transplantation and Inflammation; Novartis Institutes for Biomedical Research; Basel Switzerland

2. Hôpital de Hautepierre; Strasbourg; France

3. Laboratory and Animal Services; Novartis Institutes for Biomedical Research; Basel Switzerland

4. Metabolism and Pharmacokinetics; Novartis Institutes for Biomedical Research; Basel Switzerland

5. Technical Research and Development; Novartis Institutes for Biomedical Research; Basel Switzerland

6. Drug Metabolism and Pharmacokinetics; Novartis Institutes for Biomedical Research; Basel Switzerland

Publisher

Wiley

Subject

Pharmacology (medical),Transplantation,Immunology and Allergy

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4. CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells;Henn;Nature,1998

5. TRAF proteins in CD40 signaling;Bishop;Adv Exp Med Biol,2007

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