Challenges in using fractional excretion of sodium in the assessment of salt poisoning

Author:

Shenoy Savitha1,Bockenhauer Detlef2ORCID

Affiliation:

1. Department of General Paediatrics and Endocrinology, Leicester Children's Hospital University Hospitals of Leicester NHS Trust Leicester UK

2. UCL Department of Renal Medicine, Great Ormond Street Hospital for Children NHS Foundation Trust London UK

Abstract

AbstractAimHypernatraemia typically reflects dehydration, yet in rare instances may be caused by salt poisoning. Identifying these rare cases is a difficult challenge. Making the diagnosis of salt poisoning can have severe consequences, such as the removal of the child from its home or even prison sentences for the implicated carer. It is therefore imperative to get the diagnosis right. Guidelines for the assessment of hypernatraemia emphasise the importance of the fractional excretion of sodium to distinguish between dehydration and salt poisoning, but no generally accepted cut‐off value exists. Opinions about the diagnosis of salt poisoning in some cases consequently may differ. Here, we aim to highlight the challenges and stimulate discussion on how to improve the tools for the assessment of hypernatraemia.MethodsReport of a case of unexplained hypernatraemia in which the treating paediatrician raised the suspicion of salt poisoning.ResultsTwo consulted experts made opposing judgements about the aetiology of the observed hypernatraemia.ConclusionClear diagnostic criteria for the diagnosis of salt poisoning are lacking and more data are needed for their establishment. Without this, victims may experience further harm and carers are at risk of devastating, yet potentially erroneous accusations.

Publisher

Wiley

Subject

General Medicine,Pediatrics, Perinatology and Child Health

Cited by 3 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Issue highlights;Acta Paediatrica;2023-12-08

2. Salt poisoning in childhood—A need for paediatric assessment tools;Acta Paediatrica;2023-11-02

3. Fluid management in children with volume depletion;Pediatric Nephrology;2023-07-14

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