Estimating the predictive validity of diabetic animal models in rosiglitazone studies

Author:

Varga O. E.12,Zsíros N.3,Olsson I. A. S.1

Affiliation:

1. Laboratory Animal Science group; IBMC - Instituto de Biologia Molecular e Celular; Universidade do Porto; Porto Portugal

2. Department of Preventive Medicine; Faculty of Public Health; University of Debrecen; Debrecen Hungary

3. 1st Department of Internal Medicine; Faculty of Medicine; University of Debrecen; Debrecen Hungary

Funder

European Union and the State of Hungary, co-financed by the European Social Fund

Publisher

Wiley

Subject

Public Health, Environmental and Occupational Health,Endocrinology, Diabetes and Metabolism

Reference33 articles.

1. Species incompatibilities in the pig-to-macaque islet xenotransplant model affect transplant outcome: a comparison with allotransplantation;Graham;Xenotransplantation,2011

2. Predictive validity of animal pain models? A comparison of the pharmacokinetic-pharmacodynamic relationship for pain drugs in rats and humans;Whiteside;Neuropharmacology,2008

3. U.S. Department of Health and Human Services Food and Drug Administration Center for Drug Evaluation and Research (CDER) 2005 Guidance for industry: estimating the maximum safe starting dose in initial clinical trials for therapeutics in adult healthy volunteers http://www.fda.gov/downloads/Drugs/Guidances/UCM078932.pdf

4. World Health Organization HSI/ESD/ICTRP 2004 International Clinical Trials Registry Platform (ICTRP) http://www.who.int/ictrp/en/

5. Addressing and advancing the problem of missing data;Walton;J Biopharm Stat,2009

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