Effects of 22 Novel CYP2D6 Variants Found in the Chinese Population on the Bufuralol and Dextromethorphan MetabolismsIn Vitro-Reference-Cited by-同舟云学术

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Effects of 22 Novel CYP2D6 Variants Found in the Chinese Population on the Bufuralol and Dextromethorphan MetabolismsIn Vitro

Published:2015-09-26 Issue:3 Volume:118 Page:190-199
ISSN:1742-7835
Container-title:Basic & Clinical Pharmacology & Toxicology
language:en
Short-container-title:Basic Clin Pharmacol Toxicol

Author:

Cai Jie¹²³,Dai Da-Peng¹,Geng Pei-Wu⁴,Wang Shuang-Hu⁴,Wang Hao²,Zhan Yun-Yun²,Huang Xiang-Xin²,Hu Guo-Xin²,Cai Jian-Ping¹

Affiliation:

1. The Key Laboratory of Geriatrics; Beijing Hospital & Beijing Institute of Geriatrics; Ministry of Health; Beijing China

2. Department of Pharmacology; School of Pharmacy of Wenzhou Medical University; Wenzhou China

3. Department of Pharmacy; Traditional Chinese Medical Hospital of Wenling; Wenling China

4. The Laboratory of Clinical Pharmacy; The People's Hospital of Lishui; Lishui China

Funder

National Natural Science Foundation of China

National Health and Family Planning Commission of the People's Republic of China

Publisher

Wiley

Subject

Pharmacology,Toxicology,General Medicine

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/bcpt.12478/fullpdf

Reference45 articles.

1. Polymorphism of human cytochrome P450 enzymes and its clinical impact;Zhou;Drug Metab Rev,2009

2. The usefulness of genotyping cytochrome P450 enzymes in the treatment of depression;Dubovsky;Expert Opin Drug Metab Toxicol,2015

3. Cytochrome P450 enzymes in drug metabolism: regulation of gene expression, enzyme activities, and impact of genetic variation;Zanger;Pharmacol Ther,2013

4. New insights into the structural characteristics and functional relevance of the human cytochrome P450 2D6 enzyme;Wang;Drug Metab Rev,2009

5. Pharmacogenomics of drug-metabolizing enzymes: a recent update on clinical implications and endogenous effects;Sim;Pharmacogenomics J,2013

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