Distinct disruptions in Land's cycle remodeling of glycerophosphocholines in murine cortex mark symptomatic onset and progression in two Alzheimer's disease mouse models

Author:

Granger Matthew W.12,Liu Hui3,Fowler Caitlin F.12,Blanchard Alexandre P.12,Taylor Matthew W.12,Sherman Samantha P. M.12,Xu Hongbin12,Le Weidong34,Bennett Steffany A. L.12ORCID

Affiliation:

1. Neural Regeneration Laboratory Ottawa Institute of Systems Biology Centre for Catalysis Research and Innovation University of Ottawa Brain and Mind Research Institute Ottawa ON Canada

2. Department of Biochemistry, Microbiology, and Immunology University of Ottawa Ottawa ON Canada

3. Department of Neurology Minhang Branch Zhongshan Hospital Fudan University Shanghai China

4. Center for Clinical Research on Neurological Diseases the 1st Affiliated Hospital Dailan Medical University Dailan China

Funder

University of Ottawa

Canadian Institutes of Health Research

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Biochemistry

Reference62 articles.

1. Clinical and biomarker changes in dominantly inherited Alzheimer's disease;Bateman R. J.;N. Engl. J. Med.,2012

2. Adaptive linear step‐up procedures that control the false discovery rate;Benjamini Y.;Biometrika,2006

3. Using neurolipidomics to identify phospholipid mediators of synaptic (dys)function in Alzheimer's disease;Bennett S. A. L.;Front. Physiol.,2013

4. Neocortical neurofibrillary tangles correlate with dementia severity in Alzheimer's disease;Bierer L. M.;Arch. Neurol.,1995

5. Visualization and phospholipid identification (VaLID): online integrated search engine capable of identifying and visualizing glycerophospholipids with given mass;Blanchard A. P.;Bioinformatics,2013

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