The deadly landscape of pro-apoptotic BCL-2 proteins in the outer mitochondrial membrane

Author:

Luna-Vargas Mark P.A.12ORCID,Chipuk Jerry E.12345

Affiliation:

1. Department of Oncological Sciences; Icahn School of Medicine at Mount Sinai; New York NY USA

2. The Tisch Cancer Institute; Icahn School of Medicine at Mount Sinai; New York NY USA

3. The Diabetes, Obesity and Metabolism Institute; Icahn School of Medicine at Mount Sinai; New York NY USA

4. Department of Dermatology; Icahn School of Medicine at Mount Sinai; New York NY USA

5. The Graduate School of Biomedical Sciences; Icahn School of Medicine at Mount Sinai; New York NY USA

Funder

National Institutes of Health

JJR Foundation

William A. Spivak Fund

Fridolin Charitable Trust

American Cancer Society

Irma T. Hirschl Trust

March of Dimes Foundation

Developmental Research Pilot Project Program within the Department of Oncological Sciences at Mount Sinai

Publisher

Wiley

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference120 articles.

1. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics;Kerr;Br J Cancer,1972

2. Cell death in disease: mechanisms and emerging therapeutic concepts;Hotchkiss;N Engl J Med,2009

3. The apoptosome: signaling platform of cell death;Riedl;Nat Rev Mol Cell Biol,2007

4. Mitochondria and cell death: outer membrane permeabilization and beyond;Tait;Nat Rev Mol Cell Biol,2010

5. Apoptosome structure, assembly, and procaspase activation;Yuan;Structure,2013

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