In vivo properties of thiol inhibitors of the three vasopeptidases NEP, ACE and ECE are improved by introduction of a 7-azatryptophan in P2′ position

Author:

Inguimbert N.,Poras H.,Dhotel H.,Beslot F.,Scalbert E.,Bennejean C.,Renard P.,Fournié-Zaluski M.-C.,Roques B.-P.

Publisher

Wiley

Subject

Endocrinology,Biochemistry

Reference35 articles.

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2. Crystal structure of the human angiotensin-converting enzyme-lisinopril complex;Natesh;Nature,2003

3. Structure of human neutral endopeptidase (neprilysin) complexed with phosphoramidon;Oefner;J. Mol. Biol.,2000

4. Cell surface metallopeptidases involved in blood pressure regulation: structure, inhibition and clinical perspectives;Roques;Pathol. Biol.,1998

5. Inhibition of both angiotensin-converting enzyme and neutral endopeptidase by S21402 (RB105) in rats with experimental myocardial infarction;Gonzalez;J. Pharmacol. Exp. Ther.,1996

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