Affiliation:
1. School of Arts Beijing Language and Culture University Beijing China
2. Academy of Music, Hong Kong Baptist University Kowloon Hong Kong
3. Department of Urology Capital Medical University Beijing Friendship Hospital Beijing China
Abstract
AbstractAimsTo explore whether music intervention improves the quality of life (QOL) of patients undergoing hematopoietic stem cell transplantation (HSCT) and to evaluate its impact on patients' symptoms of depression/anxiety and fatigue.MethodsThis systematic review and meta‐analysis was conducted in accordance with the Preferred Reporting Items of Systematic reviews and Meta‐Analyses (PRISMA) guidelines. The databases PubMed, Cochrane CENTRAL, and EMBASE were searched from inception to September 30, 2022. The search strategy used a combination of the keywords “music” and “hematopoietic stem cell transplantation” or “HSCT.” The outcomes assessed were QOL, depression and anxiety, and fatigue. Pooled standardized mean differences with 95% confidence intervals were calculated to compare the outcomes between the music intervention and control groups. Heterogeneity across the studies was assessed using a chi‐square‐based test, and the I2 and Q statistics.ResultsMeta‐analysis of the included study population showed that music intervention for patients undergoing HSCT was associated with patients' improved QOL, and resulted in reduced depression/anxiety and fatigue compared to patients without music intervention.ConclusionMusic intervention benefits HSCT outcomes, including better QOL, less depression/anxiety, and less fatigue postoperatively. Future trials with larger samples are still warranted to strengthen the evidence supporting the benefits of music intervention in this patient population.