β-cell specific T-lymphocyte response has a distinct inflammatory phenotype in children with Type 1 diabetes compared with adults

Author:

Arif S.12,Gibson V. B.1,Nguyen V.1,Bingley P. J.32,Todd J. A.42,Guy C.52,Dunger D. B.52,Dayan C. M.6,Powrie J.7,Lorenc A.8,Peakman M.12

Affiliation:

1. Department of Immunobiology; King's College London; London

2. JDRF Centre for Diabetes Genes, Autoimmunity and Prevention; University of Cambridge; Cambridge UK

3. School of Clinical Sciences; University of Bristol; Bristol UK

4. JDRF/Wellcome Trust Diabetes and Inflammation Laboratory; Addenbrooke's Hospital; University of Cambridge; Cambridge UK

5. University Department of Paediatrics; Addenbrooke's Hospital; Cambridge UK

6. Institute of Molecular and Experimental Medicine; Cardiff University School of Medicine; Cardiff UK

7. Department of Diabetes and Endocrinology; Guy's & St Thomas' National Health Service (NHS) Foundation Trust; London UK

8. National Institute for Health Research; Biomedical Research Centre at Guy's and St Thomas' NHS Foundation Trust and King's College London; UK

Funder

Juvenile Diabetes Research Foundation

National Institute for Health Research

Publisher

Wiley

Subject

Endocrinology,Endocrinology, Diabetes and Metabolism,Internal Medicine

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