Evidence that Melanocortin Receptor Agonist Melanotan-II Synergistically Augments the Ability of Naltrexone to Blunt Binge-Like Ethanol Intake in Male C57BL/6J Mice

Author:

Navarro Montserrat1,Carvajal Francisca2,Lerma-Cabrera Jose Manuel2,Cubero Inmaculada3,Picker Mitchell J.1,Thiele Todd E.14

Affiliation:

1. Department of Psychology; University of North Carolina; Chapel Hill North Carolina

2. Department of Psychology; Autonoma University de Chile; Santiago Chile

3. Department of Psychology; University of Almeria; Almeria Spain

4. Bowles Center for Alcohol Studies; University of North Carolina; Chapel Hill North Carolina

Funder

National Institute of Health

Department of Defense

Publisher

Wiley

Subject

Psychiatry and Mental health,Toxicology,Medicine (miscellaneous)

Reference55 articles.

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2. Morphine down-regulates melanocortin-4 receptor expression in brain regions that mediate opiate addiction;Alvaro;Mol Pharmacol,1996

3. Analogs of MTII, lactam derivatives of alpha-melanotropin, modified at the N-terminus, and their selectivity at human melanocortin receptors 3, 4, and 5;Bednarek;Biochem Biophys Res Commun,1999

4. Inhibition of dopamine and norepinephrine reuptake produces additive effects on energy balance in lean and obese mice;Billes;Neuropsychopharmacology,2007

5. Economic costs of excessive alcohol consumption in the U.S., 2006;Bouchery;Am J Prev Med,2011

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