Comparison of Digital 12-Lead ECG and Digital 12-Lead Holter ECG Recordings in Healthy Male Subjects: Results from a Randomized, Double-Blinded, Placebo-Controlled Clinical Trial

Author:

Wang Duolao1,Bakhai Ameet2,Arezina Radivoj3,Täubel Jörg3

Affiliation:

1. Department of Clinical Sciences; Liverpool School of Tropical Medicine; Liverpool United Kingdom

2. Department of Cardiology; Barnet & Chase Farm NHS Trust; Middlesex United Kingdom

3. Richmond Pharmacology; St. George's University of London; London United Kingdom

Publisher

Wiley

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine,General Medicine

Reference18 articles.

1. ICH E14 The clinical evaluation of QT/QTc interval prolongation and proarrhythmic potential for non-antiarrhythmic drugs

2. Correction for QT/RR hysteresis in the assessment of drug-induced QTc changes-cardiac safety of gadobutrol;Malik;Ann Noninvasive Electrocardiol,2009

3. Subject-specific profiles of QT/RR hysteresis;Malik;Am J Physiol Heart Circ Physiol,2008

4. CSRC White paper: Can the thorough QT/QTc study be replaced by ‘early QT assessment’ in routine clinical pharmacology studies? Scientific update and a research proposal for a path forward;Darpo;Am Heart J,2014

5. Early QT assessment-how can our confidence in the data be improved?;Darpo;Br J Clin Pharmacol,2012

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