Design, Synthesis, and Biological Evaluation of a Novel Water-soluble Prodrug of Docetaxel with Amino Acid as a Linker-Reference-Cited by-同舟云学术

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Design, Synthesis, and Biological Evaluation of a Novel Water-soluble Prodrug of Docetaxel with Amino Acid as a Linker

Published:2016-05-24 Issue:3 Volume:88 Page:363-369
ISSN:1747-0277
Container-title:Chemical Biology & Drug Design
language:en
Short-container-title:Chem Biol Drug Des

Author:

Ma Huan¹,Chen Gang²,Wang Tao²,Li Qingeng¹,Liu Yan¹

Affiliation:

1. School of Pharmacy; Chongqing Medical University; Chongqing 400016 China

2. R&D Department; Jiangsu Nhwa Luokang Pharmaceutical Corporation Ltd.; Xu Zhou 221000 China

Funder

Shanghai Institute of MateriaMedica

Publisher

Wiley

Subject

Molecular Medicine,Biochemistry,Drug Discovery,Pharmacology,Organic Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/cbdd.12762/fullpdf

Reference17 articles.

1. Plant antitumor agents. VI. Isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia;Wani;J Am Chem Soc,1971

2. A novel controlled release formulation for the anticancer drug paclitaxel (Taxol®): PLGA nanoparticles containing vitamin E TPGS;Mu;J Controlled Release,2003

3. Polymeric nanospheres fabricated with natural emulsifiers for clinical administration of an anticancer drug paclitaxel (Taxol®);Feng;Material Sci Eng,2002

4. A lipophilic paclitaxel derivative incorporated in a lipid emulsion for parenteral administration;Lundberg;J Controlled Release,2003

5. Physico-chemical stability of docetaxel premix solution and docetaxel infusion solutions in PVC bags and polyolefine containers;Thiesen;Pharm World Sci,1999

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