2-Prenylatedm-dimethoxybenzenes as potent inhibitors of 15-lipo-oxygenase: inhibitory mechanism and SAR studies-Reference-Cited by-同舟云学术

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2-Prenylatedm-dimethoxybenzenes as potent inhibitors of 15-lipo-oxygenase: inhibitory mechanism and SAR studies

Published:2016-06-06 Issue:3 Volume:88 Page:460-469
ISSN:1747-0277
Container-title:Chemical Biology & Drug Design
language:en
Short-container-title:Chem Biol Drug Des

Author:

Jabbari Atena¹,Sadeghian Hamid²³,Salimi Alireza¹,Mousavian Mina⁴,Seyedi Seyed M.¹,Bakavoli Mehdi¹

Affiliation:

1. Department of Chemistry; Faculty of Science; Ferdowsi University of Mashhad; Mashhad Iran

2. Neurogenic Inflammation Research Center; Mashhad University of Medical Sciences; Mashhad Iran

3. Department of Laboratory Sciences; School of Paramedical Sciences; Mashhad University of Medical Sciences; Mashhad Iran

4. Department of Biology; Mashhad Branch; Islamic Azad University; Mashhad Iran

Funder

Mashhad University of Medical Sciences and Ferdowsi University

Publisher

Wiley

Subject

Molecular Medicine,Biochemistry,Drug Discovery,Pharmacology,Organic Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/cbdd.12779/fullpdf

Reference30 articles.

1. Lipoxygenases: Occurrence, Functions, Catalysis, and Acquisition of Substrate

2. Synthesis and SAR studies of 3-allyl-4-prenyloxyaniline amides as potent 15-lipoxygenase inhibitors

3. Dual inhibition of cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX) as a new strategy to provide safer non-steroidal anti-inflammatory drugs

4. Design and synthesis of eugenol derivatives, as potent 15-lipoxygenase inhibitors

5. Design and synthesis of 4-methoxyphenylacetic acid esters as 15-lipoxygenase inhibitors and SAR comparative studies of them

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1. Molecular Docking Based Study and Analysis of Phytochemicals with TNF-α in Search of Anti-Inflammatory and Anticancer Agents;Asian Journal of Organic & Medicinal Chemistry;2020

2. Altered expression level of inflammation-related genes and long-term changes in ocular surface after trabeculectomy, a prospective cohort study;The Ocular Surface;2018-10

3. A novel class of human 15-LOX-1 inhibitors based on 3-hydroxycoumarin;Chemical Biology & Drug Design;2018-02-26

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